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This gene is often a member of the SUMO gene household. This family members of genes encode tiny ubiquitin-similar modifiers which have been attached to proteins and Command the focus on proteins' subcellular localization, security, or exercise. The protein explained During this file is situated inside the cytoplasm and specifically modifies IKBA, bringing about negative regulation of NF-kappa-B-dependent transcription of your IL12B gene.
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